Sodium polystyrene sulfonate powder has been in use for over 50 years for the treatment of hyperkalemia, a condition characterized by an abnormally high level of potassium in the blood.

A cation-exchange resin, sodium polystyrene sulfonate exchanges sodium ions attached to the resin with free-floating potassium ions within the large intestine, which are then expelled through the intestinal tract.

  • Powder form used for individualized dosing
  • When compounded for suspension, this drug should be freshly prepared and not stored beyond 24 hours
  • Store at controlled room temperature, 15°-30° C (59°-86° F)
  • Available in 454 gram (1 Pound) jar
  • Manufactured at our facility in Farmville, NC

What is hyperkalemia?

Hyperkalemia is a condition in which the concentration of potassium in the blood is elevated.

While most cases of hyperkalemia are mild, severe hyperkalemia is a medical emergency and can result in sudden death through cardiac arrhythmia or irregular heartbeat. When not recognized and treated properly, severe hyperkalemia results in a mortality rate of nearly 67%. Hyperkalemia is a fairly common blood condition and is diagnosed in up to 8% of U.S. hospitalized patients.

Most cases of hyperkalemia are caused by disorders that reduce kidney function, such as diabetes and cardiovascular disease. Hyperkalemia can also be caused by bodily injury and by certain medications, including non-steroidal anti-inflammatory drugs (e.g. aspirin and ibuprofen) and ACE Inhibitors, as well as transcellular shifts of potassium into the bloodstream, often caused by metabolic acidosis.

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